2Ti 3:1 But understand this, that in the last days there will come times of difficulty.
2Ti 3:2 For people will be lovers of self, lovers of money, proud, arrogant, abusive, disobedient to their parents, ungrateful, unholy,
2Ti 3:3 heartless, unappeasable, slanderous, without self-control, brutal, not loving good,
2Ti 3:4 treacherous, reckless, swollen with conceit, lovers of pleasure rather than lovers of God,
2Ti 3:5 having the appearance of godliness, but denying its power. Avoid such people.
For people "will be" = middle voice, meaning the subject is active in this--doing it to themselves. They aren't victims. They do this to themselves up against the truth and true wisdom. So it isn't a medical issue.
This is sin and the world's "wisdom" (psychology) and medicine not only can't solve it, they actually feed the sin by avoiding any consciousness of guilt. They suppress the truth with unrighteousness. Nothing works because they are "irreconcilable", haters of good, and arrogant.